From supramolecular chemistry to the nucleosome: studies in biomolecular recognition

• Marcey L. Waters

Beilstein J. Org. Chem. 2016, 12, 1863–1869, doi:10.3762/bjoc.12.175

• -helices; aromatic interactions; β-hairpin peptides; cation–π interactions; dynamic combinatorial chemistry; histone; molecular recognition in water; nucleosome; π–π-stacking; post-translational modification; supramolecular chemistry; Review Childhood influences When thinking about how to start writing

• ][26][27][28][29][30][31][32]. At the same time, our model systems provided significant insight into the features that contribute to folding of β-hairpin peptides and β-sheets, an area that lagged decades behind the general understanding of α-helices. Beyond using β-hairpins as scaffolds for physical